Hsiu-Chuan Wei

 


Department of Applied Mathematics           Phone: +886-4-24517250 Ext. 5118

Feng Chia University                       Fax: +886-4-24510801

100, Wenhwa Rd., Seatwen,                  Email: hsiucwei@fcu.edu.tw

Taichung 40724, Taiwan

 

Education

l  Michigan State University, Ph.D. in Applied Mathematics, Aug. 2000.

l  National Tsing Hua University, Taiwan, M.E. in Industrial Engineering, June 1990.

l  National Chiao Tung University, Taiwan, B.S. in Applied Mathematics, June 1988.

 

Current Position

l  Professor, Department of Applied Mathematics, Feng Chia University, Taiwan, 2014/8-present.

Previous Positions

l  Associate Professor, Department of Applied Mathematics, Feng Chia University, Taiwan, 2010/2-2014/7.

l  Assistant Professor, Department of Applied Mathematics, Feng Chia University, Taiwan, 2002/8-2010/1.

l  Assistant Professor, Department of Digital Content Design, Tatung Institute of Technology, Taiwan, 2002/2-2002/7.

l  Post-doctoral Fellow, Institute of Mathematics, Academia Sinica, Taiwan, 2001/8-2002/2.

l  Post-doctoral Fellow, Department of Applied Mathematics, Michigan State University, 2000/8-2001/7.

l  Teaching Assistant, Department of Applied Mathematics, Michigan State University, 1994/9-2000/7.

 

Research Interests

l  Mathematical modeling of tumor growth and treatment

l  Mathematical modeling of population dynamics

l  Optimization modeling in operations research

l  Scientific computation

l  Numerical methods of bifurcations in dynamic systems and their applications in biology

 

Courses Taught

l  Instructor: Ordinary differential equations and dynamical systems, Numerical analysis, Operations research, Modeling and Simulations, Optimization Theory and Applications, Calculus,

l  Teaching Assistant: Precalculus, MSU, MI, 1995/9-2001/7.

 

Publications

 

1.        Jui-Ling Yu, Hsiu-Chuan Wei, Sophia RJ Jang, The Role of CD4+ T Cells in Oncolytic Virotherapy, Mathematical Methods in the Applied Sciences, 48(18), 2025, 16652-16668. https://doi.org/10.1002/mma.70115.

2.         P. Ambegoda, Hsiu-Chuan Wei and Sophia R-J Jang*, The role of immune cells in resistance to oncolytic viral therapy, Mathematical Biosciences and Engineering, 21(5), 2024, 5900-5946. https://doi.org/10.3934/mbe.2024261

3.         G. V. R. K. Vithanage, Hsiu-Chuan Wei and Sophia R-J Jang*, The role of tumor activation and inhibition with saturation effects in a mathematical model of tumor and immune system interactions undergoing oncolytic viral therapy, Mathematical Methods in the Applied Sciences, 2023, 1-27. https://doi.org/10.1002/mma.9152

4.         Hsiu-Chuan Wei*, Mathematical modeling of tumor growth and treatment: Triple negative breast cancer, Mathematics and Computers in Simulation, 204, 2023, 645-659. (SCI). [MOST109-2115-M-035-003].

5.         Avinash Shankaranarayanan and Hsiu-Chuan Wei*, Mathematical modeling of SARS-nCoV-2 virus in Tamil Nadu, South India, Mathematical Biosciences and Engineering, 19(11), 2022, 11324-11344. (SCI). [MOST 110-2115-M-035-004].

6.         G. V. R. K. Vithanage, Hsiu-Chuan Wei and Sophia R-J Jang*, Bistability in a model of tumor-immune system interactions with an oncolytic viral therapy. Mathematical Biosciences and Engineering, 19(2), 2022, 1559-1587. (SCI).

7.         Sophia R-J Jang* and Hsiu-Chuan Wei, On a Mathematical Model of Tumor –Immune System Interactions with an Oncolytic Virus Therapy. Discrete and Continuous Dynamical Systems Series B, 2022, 27(6), 3261-3295. doi:10.3934/dcdsb.2021184. (SCI).

8.         Jui-Ling Yu*, Hsiu-Chuan Wei, and Sophia R-J Jang, A model of tumor-immune system interactions with healthy cells and immunotherapy, Mathematical Methods in the Applied Sciences, 45, 2022, 2852-2870, DOI: 10.1002/mma.7958. (SCI).

9.         Sophia R.-J. Jang*, Hsiu-Chuan Wei, Deterministic Predator-Prey Models With

Disease in the Prey Population, Journal of Biological Systems, 28(3), 2020, 751-784.  [MOST104-2115-M-035-006]

10.     Hsiu-Chuan Wei*, Mathematical modeling of ER-positive breast cancer treatment with AZD9496 and palbociclib. AIMS Mathematics, 5(4), 2020, 3446-3455. [MOST107-2115-M-035-006]

11.     Hsiu-Chuan Wei*, Bifurcation Analysis of a Mathematical Model of Tumor

Growth in MCF-7 Breast Cancer Cell Line. EPiC Series in Computing, 70, 2020, 33-40.  [MOST108-2115-M-035-006]

12.     Hsiu-Chuan Wei*, Mathematical Modeling of Tumor Growth: the MCF-7 Breast Cancer Cell Line. Mathematical Biosciences and Engineering, 16(6), 2019, 6512-6535.  [MOST 107-2115-M-035-006]

13.     Hsiu-Chuan Wei*, A Mathematical Model of Intraguild Predation with Prey Switching. Mathematics and Computers in Simulation, 165, 2019, 107-118. https://doi.org/10.1016/j.matcom.2019.03.004.  [MOST 106-2115-M-035-004]

14.     Hsiu-Chuan Wei*, A Mathematical Model of Tumor Growth with Beddington-DeAngelis Functional Response: A Case of Cancer without Disease. Journal of Biological Dynamics, 12(1), 2018, 194-210, DOI:10.1080/17513758.2017.1418028.  [MOST 105-2115-M-035-004]

15.     Hsiu-Chuan Wei, Jui-Ling Yu*, and Chia-Yu Hsu, Periodically Pulsed Immunotherapy in a Mathematical Model of Tumor, CD4+ T Cells, and Antitumor Cytokine Interactions. Computational and Mathematical Methods in Medicine, Volume 2017, Article ID 2906282, 12 pages.

16.     Hsiu-Chuan Wei*, Jenn-Tsann Lin, Shin-Feng Hwang, Yuh-Yih Chen, “On the Codimension-Two and -Three Bifurcations of a Food Web of Four Species”, Konuralp Journal of Mathematics, 4(1), 2016, 185-192. [MOST103-2115-M-035-005]

17.     Hsiu-Chuan Wei*, “Mathematical and Numerical Analysis of a Mathematical Model of Mixed Immunotherapy and Chemotherapy of Cancer”, Discrete and Continuous Dynamical Systems Series B, 21(4), 2016, 1279-1295. [MOST103-2115-M-035-005]

18.     Yuh-Yih Chen, Jenn-Tsann Lin*, Hsiu-Chuan Wei, “Mathematical Analysis of a Class of Surface-Tension Driven Flows”, Advances in Research, 6 (3), 2016, Article no. AIR.22415, 1-8. [MOST103-2115-M-035-005]

19.     Hsiu-Chuan Wei*, “A Modified Numerical Method for Bifurcations of Fixed Points of ODE Systems with Periodically Pulsed Inputs”, Applied Mathematics and Computation, (236), 2014, 373–383. [NSC102-2115-M-035-003]

20.     Hsiu-Chuan Wei*, Jenn-Tsann Lin “Periodically Pulsed Immunotherapy in a Mathematical Model of Tumor-Immune Interaction”, Int. J. Bifurcation and Chaos, 2013, 1350068 (13 pages), DOI: 10.1142/S0218127413500685.

21.     Hsiu-Chuan Wei*, “A numerical study of a mathematical model of pulsed immunotherapy for superficial bladder cancer”, Jpn. J. Ind. Appl. Math., (30), 2013, pp. 441-452. [FCU12G27167; NSC100-2115-M-035-002]

22.     Hsiu-Chuan Wei*, “Qualitative simulation of the growth of electrolessly deposited Cu thin films”, Mathematical Problems in Engineering, 2011, Article ID 528351, 13 pages, DOI: 10.1155/2011/528351.

23.     Hsiu-Chuan Wei*, Shin-Feng Hwang, Jenn-Tsann Lin, & Tze-Jang Chen “The role of initial tumor biomass size in a mathematical model of periodically pulsed chemotherapy”, Computers and Mathematics with Applications, 61, 2011, pp. 3117-3127. [FCU10G27221]

24.     Hsiu-Chuan Wei*, “The dynamics of the Luo-Rudy model”, Int. J. Bifurcation. Chaos, 20(12), 2010, pp. 4055-4066. [NSC98-2115-M-035-003]

25.     Hsiu-Chuan Wei*, “Numerical revisit to a class of one-predator, two-prey models”. Int. J. Bifurcation. Chaos, 20(8), 2010 pp. 2521-2536. [FCU06G27163; NSC96-2115-M-035-003]

26.     Hsiu-Chuan Wei*, “On the bifurcation analysis of a food web of four species”, Applied Mathematics and Computation, 215(9) 2010 pp. 3280-3292. [NSC97-2115-M-035-003].

27.     Mo-Hong Chou*, Hsiu-Chuan Wei, & Yu-Tuan Lin, “Oregonator-based simulation of the Belousov-Zhabotinskii reaction”, Int. J. Bifurcation. Chaos, 17(12), 2007 pp. 4337-4353.

28.     Mo-Hong Chou* & Hsiu-Chuan Wei, “An anatomy of Lagrangian chaos in low Reynolds number flow between two eccentric rotating cylinders”, Int. J. Bifurcation and Chaos, 15(9), 2005, pp. 2833-2847. [NSC91-2115-M-035-005].

29.     C. Chiu* and H. Wei, “A multigrid method for pattern formation problems in biology”. Differential and Integral Equations (2003) pp.201-220.

30.      Gang Bao*, Jun Liu, & Hsiu-Chuan Wei, “Recursive Linearization of an inverse Medium Problem”, Progress in analysis, Vol. I,II (Berlin,2001), 1423-1435, World Sci. Publishing, River Edge, NJ, 2003.

31.     Y. Cheng, H. Wei, and J. Yuan*, “On Establishment of I/O tables in Automation of a Fault tree synthesis”, Reliability Engineering and System Safety 40 (1993) pp.311-318.

 

Editorial Service

   Co-Guest Editor, Mathematical Biosciences and Engineering, 2021.

Special Issue: The Application of Mathematical Models in Cancer and Cancer Therapy

   Co-Guest Editor, Mathematical Biosciences and Engineering, 2024.

Special Issue: Bridging ecological, epidemiological, and oncological models: New perspectives in population and disease dynamics

Co-Guest Editor, Mathematics, 2025.

Advances in Mathematical modeling of Biological systems: Deterministic, Stochastic, and Complex Dynamics.

 

 

Research Grants Awarded

NSTC 114-2115-M-035-002, 2025

NSTC 113-2115-M-035-005, 2024

NSTC 112-2115-M-035-006, 2023

       MOST 111_2115_M_035_003, 2022.

MOST 110_2115_M_035_004, 2021.

MOST 109_2115_M_035_003, 2020.

MOST 108-2115-M-035-006, 2019.

MOST 107-2115-M-035-006, 2018.

MOST 106-2115-M-035-005, 2017.

MOST 105-2115-M-035-004, 2016.

MOST 104-2115-M-035-006, 2015.

MOST 103-2115-M-035-005, 2014.

MOST 102-2115-M-035-003, 2013.

FCU 12G27167, 2012.

NSC 100-2115-M-035-002, 2011.

FCU 10G27221, 2010.

NSC 98-2115-M-035-003, 2009.

NSC 96-2115-M-035-003, 2007